Isolation of enterovirus 71 from patients with hand, foot and mouth disease in a local epidemic on March 2006, in Miyagi prefecture, Japan.

Enterovirus detection status of patients with herpangina and hand, foot and mouth disease in epidemic season 2007, Kanagawa Prefecture, Japan.

Epidemic of hand, foot and mouth disease in Gifu Prefecture in 1978.

During the period from May to August, 1978, an epidemic of hand, foot and mouth disease (HFMD) occurred in Gifu prefecture. Epidemiological, virological and serological investigations were performed. Cases involved ranged from 0 to 31 years of age, and 80.2% of them were under 5 years of age. The incidence of HFMD with neurological complication (3.7%) was lower than that in 1973. Enterovirus 71...

A large-scale epidemic of hand, foot and mouth disease associated with enterovirus 71 infection in Japan in 1978.

An epidemic of hand, foot and mouth disease (HFMD) took place throughout Japan in 1978. A total of 36,301 cases were reported and clinical symptoms were mostly typical of HFMD. Most patients were under five years of age. This communication deals with the summarized results of epidemiological informa tion from various laboratories on the incidence of HFMD. Enterovirus 71 is known to be associate...

Epidemic of hand, foot and mouth disease in Japan, 1972-1973: difference in epidemiologic and virologic features from the previous one.

Japan, 1969-1970, was reported in a previous publication (Tagaya and Moritsugu, 1973). In the following year, however, coxsackievirus A 16 (CA 16), the causative agent of the disease, seemed to have disappeared from the country; only one laboratory reported positive isolation of CA 16, but later it proved to have been due to misidentification as checked by the Department of Enteroviruses, Natio...

Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years

BACKGROUND A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region. Some of these outbreaks had unusually high numbers of fatalities and this generated much fear and anxiety in the region. METHODS We established a sentinel surveillance programme for hand, foot and mouth disease...